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Professor Maria Kyrgiou

MSc, PhD MRCOG

Special interests:

Gynaecological surgery, Gynaecological cancer, Endometriosis, Fibroids, Early pregnancy, Minimal access surgery, Colposcopy

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Specialist Treatments

Treatments offered at King Edward VII’s Hospital include, but are not limited to:

Hysteroscopy

Professional Biography

Professor Maria Kyrgiou is a Consultant Obstetrician and Gynaecologist at King Edward VII’s Hospital. Ms Kyrgiou has expertise in general gynaecology, minimal access surgery and gynaecology oncology. Alongside her work at King Edward VII’s Hospital, Professor Kyrgiou is an associate professor at Imperial College London.

Professor Maria Kyrgiou (MSc PhD MRCOG) completed a MSc (masters of science) in advanced gynaecological endoscopy at the University of Surrey, before completing a doctorate thesis in ovarian cancer chemotherapy. Professor Kyrgiou is recognised nationally and internationally for her research. She has been published in scientific journals and contributes to national and international committees.

She has trained in obstetrics and gynaecology and subsequently specialised in advanced minimal access surgery (laparoscopy and hysteroscopy) for complex benign disease and gynaecologic oncology at the West London Gynaecological Cancer Centre at Imperial College Healthcare NHS Trust.

Professor Kyrgiou is a keen researcher and educator. The primary focus of her research is translational research in gynaecological diseases and cancers. In particular, she focuses on cervical, endometrial and ovarian cancer with an emphasis on prevention and personalised treatment.

She has an interest in cervical pre-invasive and invasive disease, primary cervical screening and HPV vaccines. She has led research into the impact of treatment for cervical pre-invasive and early invasive cervical disease on reproductive outcomes and the clinical use of HPV biomarkers in personalising the management of women with abnormal findings at primary population-based screening. Alongside this, Professor Kyrgiou also runs a research group investigating the impact of obesity and metabolic disorders in the development of gynaecological cancers with an emphasis on endometrial cancer.

She further investigates the role of the genital tract and gut microbiome and host interactions in the development and treatment response of gynaecological cancers.

Additional Information

Publications

Kyrgiou M, Kalliala I, Markozannes G, et al., 2017, Adiposity and cancer at all anatomic sites: an umbrella review of the literature, British Medical Journal, Vol:356, ISSN:1468-5833

Mitra A, MacIntyre D, lee YS, et al., 2015, Cervical intraepithelial neoplasia disease progression is associated with increased vaginal microbiome diversity, Scientific Reports, Vol:5, ISSN:2045-2322

Theophilou G, Paraskevaidi M, Lima KMG, et al., 2015, Extracting biomarkers of commitment to cancer development: potential role of vibrational spectroscopy in systems biology, Expert Review of Molecular Diagnostics, Vol:15, ISSN:1473-7159, Pages:693-713

Papakonstantinou K, Kyrgiou M, Lyons D, et al., 2014, Management of stage Ia1 squamous cervical cancer and the importance of excision margins: a retrospective study of long-term outcome after 25 years of follow-up, American Journal of Obstetrics and Gynecology, Vol:211, ISSN:0002-9378

Kyrgiou M, Mitra A, Arbyn M, et al., 2014, Fertility and early pregnancy outcomes after treatment for cervical intraepithelial neoplasia: systematic review and meta-analysis, British Medical Journal, Vol:349, ISSN:1468-5833

Gajjar K, Ahmadzai AA, Valasoulis G, et al., 2014, Histology verification demonstrates that biospectroscopy analysis of cervical cytology identifies underlying disease more accurately than conventional screening: Removing the confounder of discordance, PLOS One, Vol:9, ISSN:1932-6203

Woo YL, Kyrgiou M, Bryant A, et al., 2012, Centralisation of services for gynaecological cancer, Cochrane Database of Systematic Reviews, ISSN:1469-493X

Arbyn M, Kyrgiou M, Simoens C, et al., 2008, Perinatal mortality and other severe adverse pregnancy outcomes associated with treatment of cervical intraepithelial neoplasia: meta-analysis, British Medical Journal, Vol:337, ISSN:1468-5833

Kyrgiou M, Salanti G, Pavlidis N, et al., 2006, Survival benefits with diverse chemotherapy regimens for ovarian cancer: Meta-analysis of multiple treatments, Journal of the National Cancer Institute, Vol:98, ISSN:0027-8874, Pages:1655-1663

Kyrgiou M, Koliopoulos G, Martin-Hirsch P, et al., 2006, Obstetric outcomes after conservative treatment for intraepithelial or early invasive cervical lesions: systematic review and meta-analysis, The Lancet, Vol:367, ISSN:0140-6736, Pages:489-498

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